Geeta Mehta

Assistant Professor

mehtagee@umich.edu

3044 NCRC, Building 28

T: (734) 763-3957

Bio

Projects

Publications


Current Projects

In vitro 3-D Ovarian Cancer Model for Understanding Interactions with Supporting Mesenchymal Stem Cells and High Throughput Drug Screening

Ovarian cancers, the leading cause of gynecological cancer mortality worldwide, have a high mortality rate of ~55%. Ovarian cancer is often undetected (due to lack of specific symptoms) until it has disseminated within the pelvis and abdomen. At such late...

Polymer based Tissue Engineering Models to Study Microenvironmental Control of HER2 Expression in Breast Cancers

Our lab is focused on creation of 3-D microenvironments by using microtechnology and biomaterials as engineering tools. The goal of this project is to develop in vitro systems where the factors of the extracellular matrix that drive metastasis of breast...

Modulation of Hematopoietic Stem Cell activity by Mechanical Stimulation

We are interested in determining if mechanical forces can impact hematopoietic stem cell (HSC) phenotypes. In the body, multipotent HSCs reside predominantly in the marrow cavities of bones in adult mammals and are localized to the osteoblast-lined endosteal niches and...